DTI has started its activities as a center for mind–body medicine and life skills education in 1995. DTI’s mission is to expand systemic approach and psychosomatic medicine in Iran and the region. Some activities of the institute are as follows: Providing individual, family, and group counseling and psychotherapy and offering personal development courses; holding individual and public transpersonal psychology workshops since 2001 in Iran, Turkey, and Germany; offering professional short-term and post-doctoral educational and research courses in psychosomatic medicine cooperatively with other universities (Albert Ludwiga University of Freiburg ans Psychosomatic Research Center of Isfahan University of Medical Sciences); publishing journals on interdisciplinary health studies: Higher health and Journal of Tan, Ravan, va Farhanf  in Persian (which has been published electronically from 2016), and International Journal of Body, Mind, & Culture cooperatively with Albert Ludwigs University and Psychosomatic Research Center of IUMS; publishing book series of Dehkadeh Salamat on systemic approach to health; researching on, developing, and executing procedures to found an integrative psychosomatic health center, “Dehkadeh Salamat” cooperatively with Albert Ludwigs University of Freiburg and Ened; cooperation in conducting national and international research projects

DTI is now establishing a branch in Tehran and is cooperating with Mashhad University of Medical Sciences and Ferdowsi University of Mashhad to establish a psychosomatic medicine clinic in Mashhad city and to support establishing a clinic in Afghanistan cooperatively with Psychosomatic Research Center of IUMS under supervision of Albert-Ludwigs University. DTI is also working on to establish a psychosomatic clinic in Kashan.